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Primary malignant lymphoma of the brain
E Kosno-Kruszewska1, T Wierzba-Bobrowicz, G M Szpak
1Department of Neuropathology, Institute of Psychiatry and Neurology, Warszawa.
Folia Neuropathologica
|January 1, 1996
Summary
A rare primary brain lymphoma in the temporal lobe was diagnosed in a 66-year-old man. Despite treatment, the patient succumbed to the malignant, non-operative brain tumor within a year.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Primary brain lymphoma is a rare central nervous system malignancy.
- Early diagnosis is crucial for effective management.
Observation:
- A 66-year-old male presented with symptoms including dizziness, aphasia, and hemiparesis.
- Computed tomography (CT) scans revealed a temporal lobe brain tumor.
- The tumor was histopathologically confirmed as a B-cell malignant lymphoma with T-cell presence.
Findings:
- The patient received radiotherapy and steroid therapy for the malignant, non-operative brain tumor.
- Despite treatment, the patient died 12 months after symptom onset.
- Autopsy confirmed the tumor as a primary brain lymphoma, with no evidence of systemic disease.
Implications:
- This case highlights the diagnostic challenges and aggressive nature of primary brain lymphoma.
- Further research into novel therapeutic strategies for primary brain lymphoma is warranted.
- Understanding the immunophenotype is critical for accurate diagnosis and potential targeted therapies.