Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell-cell interaction and tissue factor expression

R Lorenzet1, E Napoleone, A Celi

  • 1Department of Vascular Medicine and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, Santa Maria Imbaro, Italy. lorenzet@cmns.mnegri.it

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|November 18, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probing supersolidity through excitations in a spin-orbit-coupled Bose-Einstein condensate.

Science (New York, N.Y.)·2026
Same author

Distribution of TAS2R38 bitter taste receptor phenotype and haplotypes among COVID-19 patients.

Scientific reports·2022
Same author

The efficacy of myofunctional therapy in patients with atypical swallowing.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2020
Same author

Preclinical study for treatment of hypospadias by advanced therapy medicinal products.

World journal of urology·2019
Same author

A new method to assess foveal morphology with optical coherence tomography.

La Clinica terapeutica·2019
Same author

Approaches for Effective Clinical Application of Stem Cell Transplantation.

Current transplantation reports·2018
Same journal

Pampiniform venous plexus thrombosis in a 37 years-old male patient with severe thrombocytosis: a multifactorial aetiology.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
Same journal

PROS1 Cys475Tyr mutation associated with a type III protein S deficiency pattern.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
Same journal

Dynamic microclot profiling: thromboelastography advances precision management in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
Same journal

Genetic characterization of Glanzmann thrombasthenia: insights from novel igta2b mutations in a Tunisian patient cohort.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
Same journal

Uterine fibroids as an underrecognized risk factor for venous thromboembolism: a narrative review.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
Same journal

SEER sonorheometry enhances fibrinolysis detection during liver transplantation with heparin.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2026
See all related articles

Tissue factor initiates blood clotting after injury. This review explores how platelets, monocytes, and endothelial cells interact to express tissue factor, impacting vascular disease development.

Area of Science:

  • Biomedical Science
  • Vascular Biology
  • Hemostasis

Background:

  • Tissue injury exposes thrombogenic subendothelial tissue.
  • Tissue factor (TF) initiates the coagulation cascade.
  • Platelets, monocytes, and endothelial cells interact at injury sites.

Purpose of the Study:

  • To review the role of cell interactions in TF expression.
  • To explore the relevance of TF in vascular disease pathogenesis.

Main Methods:

  • Literature review of studies on TF expression and cell interactions.
  • Analysis of biochemical pathways modulated by cell-cell adhesion.

Main Results:

  • TF is expressed by vascular wall cells and activated monocytes/endothelial cells.

Related Experiment Videos

  • Cell-cell adhesion molecules regulate interactions between platelets, monocytes, and endothelial cells.
  • These interactions influence TF expression and coagulation.

    • Conclusions:

    • Cellular interactions are critical for TF expression following vascular injury.
    • Understanding these interactions is key to addressing TF's role in vascular diseases.