Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anesthesia for the micropremie

J P Spaeth1, I B O'Hara, C D Kurth

  • 1Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, and the University of Pennsylvania School of Medicine, 19104, USA.

Seminars in Perinatology
|November 20, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Does intranasal dexmedetomidine provide adequate plasma concentrations for sedation in children: a pharmacokinetic study.

British journal of anaesthesia·2018
Same author

A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles.

Anesthesia and analgesia·2001
Same author

A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. II. Perioperative breathing patterns in neonates and infants with pyloric stenosis.

Anesthesia and analgesia·2001
Same author

Desflurane confers neurologic protection for deep hypothermic circulatory arrest in newborn pigs.

Anesthesiology·2001
Same author

Impact of inspired gas mixtures on preoperative infants with hypoplastic left heart syndrome during controlled ventilation.

Circulation·2001
Same author

Cerebral oxygen saturation before congenital heart surgery.

The Annals of thoracic surgery·2001
Same journal

Congenital cytomegalovirus: Screening strategies and diagnostic challenges.

Seminars in perinatology·2026
Same journal

The society for neonatal nutrition and lifelong health: Building science and translating research to inform neonatal nutritional care.

Seminars in perinatology·2026
Same journal

Enteral nutrition to optimize health and neurodevelopmental outcomes in very preterm infants.

Seminars in perinatology·2026
Same journal

Standardizing outcome measures in preterm infant nutrition research: Use of anthropometry and body composition in the neonatal intensive care unit.

Seminars in perinatology·2026
Same journal

A dilemma of parental inclusion? Parent perspectives of NICU feeding practices and neonatal nutritional research.

Seminars in perinatology·2026
Same journal

Maternal diet and nutritional status during pregnancy and lactation: a review of implications on milk composition and lactation outcomes.

Seminars in perinatology·2026
See all related articles

Anesthesia for micropremies requires special care due to immature organ systems, increasing complication risks. Dosing and timing of anesthetic drugs must differ from full-term neonates for safety.

Area of Science:

  • Anesthesiology
  • Neonatal Medicine
  • Pediatric Surgery

Background:

  • Micropremature infants possess immature organ systems, including the airway, lungs, cardiovascular system, liver, kidneys, and central nervous system.
  • These physiological immaturities predispose micropremies to a higher risk of anesthetic complications compared to full-term neonates.
  • Immature respiratory control and mechanisms heighten the likelihood of intraoperative and postoperative apnea, hypoxemia, and hypercapnia.

Purpose of the Study:

  • To outline critical anesthetic considerations specific to micropremature infants undergoing common surgical procedures.
  • To highlight the unique physiological challenges posed by micropremies during anesthesia.
  • To emphasize the differences in anesthetic drug administration and timing required for micropremies versus full-term neonates.

Related Experiment Videos

Main Methods:

  • Review of anesthetic management strategies for micropremature infants.
  • Analysis of physiological differences between micropremies and full-term neonates relevant to anesthesia.
  • Description of anesthetic protocols for common surgical procedures in micropremies.

Main Results:

  • Micropremies exhibit increased susceptibility to anesthetic complications due to immature organ systems.
  • Anesthetic drugs can depress myocardial contractility and impair baroreflexes, elevating the risk of hypotension.
  • Slow drug metabolism and reduced drug requirements for the central nervous system necessitate adjusted dosing and timing.

Conclusions:

  • Anesthetic management for micropremies demands a tailored approach, differing significantly from that of full-term neonates.
  • Careful consideration of the micropremie's immature physiology is crucial for mitigating anesthetic risks.
  • Specific anesthetic protocols are essential for ensuring the safety and efficacy of procedures in this vulnerable population.