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Lentiviruses as gene transfer agents for delivery to non-dividing cells

L Naldini1

  • 1Cell Genesys, Foster City, CA, USA. luigin@cellgenesys.com

Current Opinion in Biotechnology
|November 20, 1998
PubMed

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...