Related Experiment Videos
Midbrain regions for eliciting vocalization by electrical stimulation in anesthetized dogs
K Liu1, N P Solomon, E S Luschei
1Department of Speech Pathology and Audiology and the National Center for Voice and Speech, The University of Iowa, Iowa City 52242, USA.
The Annals of Otology, Rhinology, and Laryngology
|November 21, 1998
Summary
Researchers mapped midbrain vocalization sites in dogs using electrical stimulation. This canine stereotaxic map aids laryngeal and respiratory physiology studies by locating specific vocalization-inducing brain regions.
Area of Science:
- Neuroscience
- Physiology
Background:
- Midbrain stimulation in anesthetized dogs is crucial for laryngeal and respiratory physiology research.
- A precise canine stereotaxic map is needed to identify midbrain vocalization sites.
Purpose of the Study:
- To construct a canine stereotaxic map for locating midbrain stimulus sites that elicit vocalization.
- To correlate vocalization sites with other motor responses in the canine midbrain.
Main Methods:
- Electrical stimulation was applied to 1,158 sites in the midbrains of 8 anesthetized dogs using currents of 1.5 mA or less.
- Vocalization and other motor responses were systematically recorded at each stimulus site.
Main Results:
- Vocalization was elicited at 213 of the stimulated sites.
- The highest probability for vocalization occurred at sites 6-10 mm anterior, 6-7 mm lateral, and 5-8 mm dorsal to earbar zero.
- Vocalization sites likely involve axons from the periaqueductal gray projecting through the tegmentum, with low-threshold sites near the medial lemniscus.
Conclusions:
- A detailed canine stereotaxic map for midbrain vocalization sites has been established.
- This map provides valuable anatomical reference for neurophysiological studies involving canine vocalization.
- The findings offer insights into the neural pathways controlling vocalization originating in the midbrain.