[Indices of immunity to endotoxin of gram-negative bacteria in intestinal dysbacteriosis]
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Updated: Oct 27, 2026

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
Published on: June 15, 2018
L I Kochurko1, V G Likhoded, E A Lobova
1Research Institute of Human Morphology, Moscow, Russia.
Abstract:
The examination of 52 patients with different forms of intestinal dysbacteriosis revealed a considerable decrease in the indices of immunity to endotoxin of gram-negative bacteria. In particular, a decrease in the content of antibodies to chemotype Re glycolipid, as well as in the content of polymorphonuclear leukocytes binding antibodies in the blood stream of the examined patients and leukocytes capable of binding endotoxin in endotoxin-treated blood smears, was registered, which was indicative of the loss of endotoxin binding reserves by leukocytes.
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