[Multiple organ insufficiency in destruction of soft tissues]

The authors report an analysis of 418 case records of patients with multiorganic insufficiency (MOI) due to extensive destruction of soft tissues as a result of prolonged, short-time or position compression, protracted arterial major blood-flow disturbances. Basic changes in the organism in endotoxemia and MOI are cuttined. Effectiveness of combined local and general treatment of patients in different periods of illness is considered. Unfavourable results obtained in usage of early stripe incisions in areas of soft tissues' damage made the authors to give up this type of surgical procedure. For prophylaxis and increase of effectiveness in treatment of MOI early revealing of soft tissues destruction is obligatory, especially in patients in critical conditions with concomitant injury and open fractures of bones. Effectiveness in treatment of MOI by extracorporeal methods of detoxication and correction of hemostasis, photo--and chemotherapy is shown. General mortality rate made up 9.1%.