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[Lymphoma lymphoplasmocytoides: a case report]
J Dwilewicz-Trojaczek1, A Kendziorek, E Paprocka
1Kliniki Chorb Wewnetrznych i Hematologii AM w Warszawie.
Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|November 24, 1998
Summary
This study details clinical symptoms and blood disorders in 82 patients with advanced lymphoplasmacytic lymphoma (LPL). Key findings include frequent lymph node enlargement, anemia, and thrombocytopenia in stage IV LPL patients.
Area of Science:
- Hematology
- Oncology
- Pathology
Context:
- Lymphoplasmacytic lymphoma (LPL) is a B-cell malignancy.
- This study focuses on patients diagnosed with advanced-stage (Stage IV) LPL.
- Bone marrow involvement is a characteristic feature in advanced LPL.
Purpose:
- To present the clinical manifestations and hematological abnormalities in patients with lymphoplasmacytic/lymphoplasmocytoidal lymphoma.
- To characterize the common symptoms and laboratory findings in advanced-stage LPL.
Summary:
- Eighty-two patients with Stage IV LPL (median age 63) were analyzed.
- Peripheral lymphadenopathy (86%) and abdominal lymphadenopathy (21%) were most common.
- Hematological issues included anemia (35%) and thrombocytopenia (38%).
- Splenomegaly (55%) and hepatomegaly (49%) were prevalent.
- Dermatoses (33%) and secondary malignancies (7%) were also observed.
Impact:
- Provides a comprehensive overview of clinical and hematological features in advanced LPL.
- Highlights the high incidence of bone marrow invasion and associated cytopenias.
- Informs clinical management and diagnostic approaches for LPL patients.