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[Vitreo-retinal complications of hemoglobinopathy SC]
P A Ndiaye1, P A Ndoye, C Seye
1Clinique Ophtalmologique CHU Le Dantec-Dakar, Sénégal.
Dakar Medical
|November 25, 1998
Summary
Sickle cell disease (SCD) patients with SC hemoglobinopathy often develop serious ocular complications. Fluorescein angiography aids in early diagnosis and preventive laser treatment for these vascular retinal issues.
Area of Science:
- Ophthalmology
- Hematology
- Medical Imaging
Background:
- Sickle hemoglobinopathies are prevalent in individuals of Black descent.
- SC hemoglobinopathy, a double heterozygous form, typically presents with milder systemic symptoms but frequently causes ocular complications.
Purpose of the Study:
- To investigate the prevalence and characteristics of ocular complications in patients with SC hemoglobinopathy.
- To evaluate the utility of fluorescein angiography in diagnosing and managing these complications.
Main Methods:
- Twenty patients with confirmed SC hemoglobinopathy (via hemoglobin electrophoresis) underwent clinical examination and fluorescein angiography.
- Treatment decisions (laser therapy or cryotherapy) were based on observed lesion features.
Main Results:
- Vascular retinal complications were identified in 75% of cases.
- Vitreous hemorrhage occurred in 10% of patients.
- Fluorescein angiography revealed findings not apparent during standard fundus examination, highlighting its diagnostic value.
Conclusions:
- Fluorescein angiography is crucial for the early detection of vascular retinal complications in SC hemoglobinopathy.
- This imaging technique enables timely, preventive laser treatment, potentially mitigating severe visual impairment.