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[Minimally invasive techniques make fetal surgery possible. Disabling abnormalities can be corrected]
T H Bui1, J A Deprest, Y Ville
1Institutionen för molekylär medicin, Karolinska sjukhuset, Stockholm.
Lakartidningen
|November 27, 1998
Summary
Prenatal diagnosis advances enable in utero-treatment for fetal abnormalities. This review covers ultrasound-guided invasive fetal therapies, including stem cell transplantation, and future prospects.
Area of Science:
- Perinatology
- Fetal Medicine
- Interventional Radiology
Context:
- Advances in fetal knowledge and prenatal diagnostic capabilities.
- Increasing instances of treating detected fetal abnormalities.
- Need for in utero-treatment for specific structural defects to prevent sequelae.
Purpose:
- To review the current status of ultrasound-guided invasive fetal therapy.
- To outline future prospects and developments in the field.
Summary:
- The review covers various ultrasound-guided invasive fetal therapies: multifetal pregnancy reduction, amniotic fluid manipulation, drainage/shunting, fetal transfusion, operative fetoscopy, and in utero stem cell transplantation.
- While most fetal malformations are managed post-delivery, some require intrauterine intervention.
- The article discusses the evolving landscape of fetal interventions.
Impact:
- Provides a comprehensive overview of current invasive fetal therapies.
- Highlights the potential for improved fetal outcomes through intrauterine interventions.
- Informs future research and clinical practice in fetal medicine.