An evaluation of new agents in the treatment of type 2 diabetes

Several new medications for the treatment of hyperglycemia for patients with type 2 diabetes have been introduced in the past several years. Integration of these medications into practice has increased the complexity of therapeutic decisions. Appropriate use of these medications increases the likelihood that patients will achieve recommended treatment goals. Many new combinations of oral medications or oral medications and insulin injections are possible. This paper reviews the pharmacology and clinical effectiveness of medications for the treatment of type 2 diabetes and provides a framework to assist with treatment decisions.