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[Willebrand disease]

C Rothschild1

  • 1Centre d'hémophilie F-Josso, hôpital Necker-Enfants malades, Paris, France.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|December 4, 1998
PubMed
Summary
This summary is machine-generated.

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Von Willebrand disease, the most common inherited bleeding disorder, requires pre-surgical evaluation due to bleeding risks. Treatment options like DDAVP must be considered for surgical or bleeding management.

Area of Science:

  • Hematology
  • Genetics
  • Internal Medicine

Context:

  • Von Willebrand disease (VWD) is the most prevalent inherited bleeding disorder, affecting approximately 1% of the population.
  • The moderate form of VWD accounts for about 80% of cases, highlighting its clinical significance.

Purpose:

  • To emphasize the critical need for pre-operative investigation of Von Willebrand disease.
  • To guide therapeutic choices, particularly the consideration of DDAVP, for managing surgical bleeding or severe hemorrhage in VWD patients.

Summary:

  • Von Willebrand disease is a common congenital bleeding disorder, with the moderate form being most frequent.
  • Pre-operative assessment for VWD is essential due to significant intraoperative and postoperative bleeding risks.
  • Evaluating the use of DDAVP is crucial for optimal surgical and bleeding management in affected individuals.

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Impact:

  • Improved patient safety through proactive management of bleeding risks associated with Von Willebrand disease.
  • Informed therapeutic decision-making for surgical procedures and severe bleeding episodes in patients with VWD.