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Electronic access to mouse tumor data: the Mouse Tumor Biology Database (MTB) project
C J Bult1, D M Krupke, J T Eppig
1The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA. cjb@informatics.jax.org
Nucleic Acids Research
|December 10, 1998
Summary
The Mouse Tumor Biology (MTB) Database offers comprehensive data on mouse cancer models, including tumor classifications, genetic factors, and pathology. This resource aids researchers in selecting models and understanding cancer development.
Area of Science:
- Oncology
- Genetics
- Bioinformatics
Background:
- The mouse is a crucial model organism for studying hereditary and induced cancers.
- Efficient access to comprehensive tumor data is essential for cancer research.
Purpose of the Study:
- To provide a centralized electronic resource for mouse cancer model data.
- To support researchers in selecting appropriate models and identifying genetic factors in cancer.
Main Methods:
- Compilation of tumor names, classifications, incidence, and latency data.
- Inclusion of tumor pathology reports, images, and genetic information.
- Integration of published and unpublished references and hypertext links to related databases.
Main Results:
- The Mouse Tumor Biology (MTB) Database offers electronic access to diverse cancer-related data.
- MTB facilitates research in model selection, mutation pattern analysis, and gene identification.
- The database provides links to external resources for enhanced data exploration.
Conclusions:
- The MTB Database serves as a valuable tool for the cancer research community.
- It enhances the utility of mouse models in understanding cancer biology.
- Accessible online, MTB supports a wide range of cancer research applications.