Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Update of the Human MitBASE database

M Attimonelli1, J M Cooper, D D'Elia

  • 1Dipartimento di Biochimica e Biologia Molecolare, Università degli Studi di Bari, 70126 Bari, Italy.

Nucleic Acids Research
|December 10, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of ambroxol on the autophagy-lysosome pathway and mitochondria in primary cortical neurons.

Scientific reports·2018
Same author

Practical recommendations for the process of proposing, planning and writing a neurological management guideline by EAN task forces.

European journal of neurology·2015
Same author

The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes, part 2.

AJNR. American journal of neuroradiology·2014
Same author

The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes, part 1.

AJNR. American journal of neuroradiology·2014
Same author

Early L-dopa, but not pramipexole, restores basal ganglia activity in partially 6-OHDA-lesioned rats.

Neurobiology of disease·2013
Same author

Chloroplast DNA variation in the grass tribe Festuceae.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
See all related articles

Human MitBASE is an updated database for human mitochondrial DNA (mtDNA) variants. It now features improved data structure, quality, and quantity, enhancing research into population polymorphisms and pathologies.

Area of Science:

  • Genomics
  • Bioinformatics
  • Human Genetics

Background:

  • Mitochondrial DNA (mtDNA) variants are crucial for understanding human population genetics and diseases.
  • Existing databases require continuous updates for data structure, quality, and quantity to support research.

Purpose of the Study:

  • To report recent improvements to the Human MitBASE database, focusing on data structure, quality, and quantity.
  • To enhance the usability and comprehensiveness of human mtDNA variant data for researchers.

Main Methods:

  • Database structure redesign and implementation.
  • Optimization of data input and quality control processes.
  • Integration of cross-references with external biological databases (EMBL, OMIM, MEDLINE).

Related Experiment Videos

Main Results:

  • The Human MitBASE database structure is fully designed and implemented.
  • Data quality and quantity have been significantly improved.
  • Approximately 5000 variants related to population polymorphisms and pathologies are currently included.

Conclusions:

  • The enhanced Human MitBASE database provides a more robust resource for studying human mtDNA variations.
  • Improved data accessibility and integration facilitate research into mtDNA-related population studies and diseases.