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The PROSITE database, its status in 1999

K Hofmann1, P Bucher, L Falquet

  • 1MEMOREC, Stoffel GmbH, Stoeckheimer Weg 1, D-50829 Koeln, Germany, Swiss Institute of Bioinformatics (SIB), Swiss Institute for Experimental Cancer Research (ISREC), CH-1066 Epalinges/Lausanne, Switzerland.

Nucleic Acids Research
|December 10, 1998
PubMed
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This summary is machine-generated.

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The PROSITE database provides protein patterns and profiles for identifying protein families and domains. Computational tools use these resources to classify new protein sequences accurately.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Protein Science

Background:

  • The PROSITE database is a crucial resource for protein sequence analysis.
  • It contains biologically significant patterns and profiles.

Purpose of the Study:

  • To describe the PROSITE database and its utility.
  • To highlight its role in protein family and domain identification.

Main Methods:

  • Utilizing computational tools for sequence analysis.
  • Applying PROSITE patterns and profiles for classification.

Main Results:

  • PROSITE aids in determining the known protein family of a new sequence.
  • It helps identify known domains within protein sequences.

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Conclusions:

  • PROSITE is an essential tool for protein sequence annotation.
  • It facilitates the understanding of protein function and evolution through domain identification.