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InBase, the New England Biolabs Intein Database

¹New England Biolabs, Inc., 32 Tozer Road, Beverly, MA 01915, USA. perler@neb.com

Nucleic Acids Research

|December 10, 1998

Summary

Inteins are protein sequences that self-splice. InBase is a comprehensive database detailing inteins, their host proteins, and related research, aiding scientific discovery.

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Area of Science:

Molecular Biology
Bioinformatics

Background:

Inteins are protein subsequences mediating protein splicing.
Understanding intein diversity and function is crucial for protein engineering.

Purpose of the Study:

To introduce InBase, a comprehensive online database for inteins.
To consolidate information on inteins and their host proteins.

Main Methods:

Development of an online database (InBase) by New England Biolabs.
Inclusion of an Intein Registry, detailed intein/host protein information, and comparative data.
Compilation of a comprehensive bibliography.

Main Results:

InBase provides a centralized resource for intein research.
The database includes tabulated comparisons and extensive literature references.
It serves as a valuable tool for scientists studying protein splicing.

Conclusions:

InBase enhances accessibility to intein-related data.
The database facilitates research in molecular biology and biotechnology.
It supports the ongoing study and application of inteins.

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