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Change in susceptibility of group B streptococci to penicillin G from 1968 through 1975
Antimicrobial Agents and Chemotherapy
|August 1, 1976
Abstract:
This report describes a study of 212 isolates of group B streptococci from sore throats over an 8-year period. A small but increasing percentage showed increased resistance to penicillin G when tested in an in vitro system.
Insights
Group B streptococci causing sore throats show a growing resistance to penicillin G. This in vitro study tracked resistance trends over eight years in 212 bacterial isolates.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Group B Streptococcus (GBS) is a significant pathogen.
- Sore throat infections can be caused by various bacteria, including GBS.
- Penicillin G is a primary antibiotic for treating streptococcal infections.
Purpose of the Study:
- To investigate the antimicrobial susceptibility of GBS isolates from sore throats.
- To determine if resistance to penicillin G has increased over time.
Main Methods:
- Collection and culture of 212 GBS isolates from patients with sore throats over an 8-year period.
- In vitro susceptibility testing of GBS isolates against penicillin G.
Main Results:
- A small but notable percentage of GBS isolates exhibited increased resistance to penicillin G.
- The observed resistance to penicillin G showed an increasing trend over the study period.
Conclusions:
- The findings suggest a potential emerging challenge in treating GBS-related sore throats with penicillin G.
- Continued surveillance of GBS antimicrobial resistance is crucial for effective clinical management.