Related Experiment Videos
Clinical trials and therapy
1Department of Neurology and Neurosurgery, McGill University, Verdun, Quebec, Canada.
Current Opinion in Neurology
|December 16, 1998
Abstract:
Parallel-group studies have established the efficacy of cholinesterase inhibitors in Alzheimer's disease, at least for short-term cognitive and clinical global enhancement. Noncognitive outcomes are currently under scrutiny. Time to reach clinical milestones may be a more useful trial design for new studies aiming to delay appearance or progression of disease.