[Cryptococcosis of the central nervous system]

A case of cryptococcosis of the brain in a male patient 47 years of age is described. Duration of the disease--about one year. Clincally it was accompanied by epileptic seizures with loss of consciousness. Diagnosis of cryptococcosis was made following the histological investigation of a part of the brain removed in connection with tumour. Morphologically, there was detected an area of necrosis and aggregation of yeast-like fungi with the typical of cryptococcus oval form and felatinous capsule showing intensive colouration when stained by Hochkiss' method. The pathogenic agent was detected in the spinal fluid of the patient and in the tissue culture.