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Updated: Aug 10, 2026

Transcriptomic Analysis of Human Retinal Surgical Specimens Using jouRNAl
Published on: August 14, 2013
Chromosomal localization and genomic organization of the human retinal rod Na-Ca+K exchanger
J E Tucker1, R J Winkfein, S K Murthy
1Department of Biochemistry & Molecular Biology, and the MRC Group on Ion Channels/Transporters, Faculty of Medicine, University of Calgary, Canada.
Abstract:
The retinal rod Na-Ca+K exchanger is a unique calcium extrusion protein found only in the outer segments of retinal rod photoreceptors. Rod Na-Ca+K exchanger cDNA (NCKX1) has been cloned from bovine and human retinas. Here, we have used fluorescent in situ hybridization and radiation hybrid mapping to localize the human NCKX1 gene to chromosome 15q22. We have determined the genomic organization of human rod NCKX1 and found one intron in the 5' untranslated region and eight introns within the coding region.
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