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[Clinical study on effect of bushen shengxue paste in treating renal anemia patients]
Abstract
Objective:
To evaluate the therapeutical mechanism of Bushen Shengxue Paste (BSSXP) on anemia.
Methods:
Chronic renal failure induced anemia patients were treated with BSSXP, clinical manifestation, anemia and renal function as indicators were observed in patients. The erythropoietin (EPO) and inhibition of colony-forming unit-erythrocyte (CFU-E) in patients' serum were determined by CFU-E in vitro.
Results:
The patients' symptoms, renal function and anemia were improved after administration with BSSXP 1-2 course. EPO in serum was slightly increased. The inhibition of CFU-E in patient's serum was significantly decreased.
Conclusions:
BSSXP could improve the anemia degree, its mechanism might be through clearing the inhibitor of CFU-E in serum.