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Updated: Aug 19, 2026

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
Published on: July 1, 2011
Identification and functional characterization of the Neisseria gonorrhoeae lbpB gene product
G D Biswas1, J E Anderson, C J Chen
1Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill 27599, USA. gdbis@med.unc.edu
Abstract:
We cloned lbpB, encoding a predicted 80-kDa lipoprotein, upstream of lbpA. A nonpolar mutant (LbpB- LbpA+) had normal lactoferrin (LF) binding and grew normally with LF as an iron source, whereas LbpB- LbpA- and LbpB+ LbpA- strains had reduced binding of LF and did not grow with LF as an iron source. LbpB bound LF directly in an affinity purification, suggesting that LbpB might play a still-uncharacterized role in the LF iron utilization.
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