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Persistent keratoacanthoma: challenges in management

G C Canas1, K J Robson, C J Arpey

  • 1Department of Dermatology, University of Iowa Hospitals, Iowa City 52242.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|December 29, 1998
PubMed
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Persistent keratoacanthoma, a challenging skin neoplasm, can be difficult to diagnose and manage. Oral isotretinoin offers a successful treatment option, leading to long-term remission in persistent cases.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Persistent keratoacanthoma presents diagnostic and management challenges.
  • Variable efficacy of current treatment modalities necessitates further investigation.
  • Early and accurate diagnosis is crucial for effective management.

Observation:

  • A case of persistent keratoacanthoma with an initially elusive diagnosis and challenging management is presented.
  • The diagnostic and therapeutic process involved multiple interventions.
  • Clinicopathologic presentation was carefully reviewed.

Findings:

  • Successful treatment was achieved with oral isotretinoin.
  • Long-term remission was maintained with a tapered dosage regimen.
  • Isotretinoin demonstrated efficacy in managing persistent keratoacanthoma.

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Implications:

  • This case highlights the clinical conundrum of persistent keratoacanthoma.
  • Understanding treatment options is key to successful outcomes.
  • Reviewing clinicopathologic features aids in managing challenging cases.