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[Electromyogram (EMG) and muscle biopsy in patients with chronic spinal muscular atrophy]
1Department of Neurological, Xiangya Hospital, Hunan Medical University, Changsha.
Hunan Yi Ke Da Xue Xue Bao = Hunan Yike Daxue Xuebao = Bulletin of Hunan Medical University
|January 1, 1997
Abstract:
The clinicopathological changes were investigated by electromyogram (EMG) and muscle biopsy in 30 cases of chronic spinal muscular atrophy. The results showed that the denervating changes were demonstrated in EMG in all patients but two. The light microscope discovered manifestation of neurogenic atrophy, and the electron microscope revealed a reduction of myofibrils, thickening and wavy appearance of Z-lines and dilation of mitochondria and endoplasmic reticula.