[Which fractionation and radiation dose for non-small-cell bronchial cancers?]

The optimal radiation schedule (dose, fractionation, volume) must be adapted to the goal of the treatment: cure with radiation alone or a radiochemotherapy approach or palliation. The former implies to deliver a dose of 60 Gy or more in 6 weeks or an equivalent biological doses. This approach should take into account the different prognostic factors (tumor size, extension...) and the technical possibilities (volume of normal tissue irradiated). Doses above 70 Gy should still be reserved for clinical investigation (conformal radiotherapy).