Related Experiment Videos
cDNA cloning, tissue distribution and chromosomal localization of the human ID4 gene
M Rigolet1, T Rich, M S Gross-Morand
1U383 INSERM, Clinique Maurice Lamy, Hôpital Necker, Université Paris V, France. rigolet@lovelace.infobiogen.fr
Abstract:
A cDNA e encoding the human Id4 protein has been isolated from an astrocytoma library. The predicted protein product shares 98% identity with the mouse Id4 protein and is markedly different from that already reported. By FISH analysis, the human ID4 gene was more precisely mapped to chromosome 6p22.3-p23. Northern blot analysis showed that ID4 is mainly expressed in thyroid, brain and fetal tissue and in some nervous system tumor cell lines.