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Modeling, synthesis and biological activity of novel antifungal agents (1)
T Tsukuda1, Y Shiratori, M Watanabe
1Department of Medicinal Chemistry, Nippon Roche Research Center, Kamakura, Japan.
Bioorganic & Medicinal Chemistry Letters
|January 5, 1999
Abstract:
Homology modeling of candida lanosterol C-14 demethylase, synthesis and in vitro antifungal activities of cyclohexyl analogs of restricticin are described.
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