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Solitary rectal ulcer syndrome
C J Vaizey1, J B van den Bogaerde, A V Emmanuel
1Middlesex Hospital, London, UK.
The British Journal of Surgery
|January 6, 1999
Summary
Solitary rectal ulcer syndrome (SRUS) is a rare rectal disorder. Behavioral therapy and surgery offer the best treatment outcomes for SRUS patients.
Area of Science:
- Gastroenterology
- Colorectal Surgery
Background:
- Solitary rectal ulcer syndrome (SRUS) is a rare condition.
- Characterized by rectal wall erythema or ulceration, specific histology, and disturbed defecation with blood and mucus passage.
Purpose of the Study:
- To review the literature on solitary rectal ulcer syndrome.
- To understand its pathogenesis, histological features, and treatment outcomes.
Main Methods:
- Literature search using Medline database.
- Manual cross-referencing of relevant studies.
Main Results:
- Pathogenesis may involve straining, digital trauma, or neuromuscular issues.
- Characteristic histology includes muscularis mucosa extension and muscularis propria disorganization.
- Biofeedback retraining and abdominal rectopexy show symptom improvement in many patients, though ulceration may persist.
Conclusions:
- Behavioral therapy and surgical interventions provide optimal treatment results for SRUS.
- Further research is needed on psychological, neuromuscular, and vascular factors.