Related Experiment Video
Updated: Aug 5, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Colo-colic intussusception in Henoch-Schönlein purpura
C K Choong1, R M Kimble, P Pease
1Department of Paediatric Surgery, Starship Children's Hospital, Auckland, New Zealand.
Henoch-Schonlein purpura (HSP) can cause intussusception, a serious complication. Colo-colic intussusception is exceptionally rare in HSP, unlike typical ileo-colic cases in idiopathic intussusception.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Immunology
Background:
- Henoch-Schonlein purpura (HSP) is a common vasculitis in children.
- Intussusception is a known, albeit infrequent, surgical complication of HSP.
Observation:
- Colo-colic intussusception is a rare presentation of intussusception in children with HSP.
- Only three previous cases of colo-colic intussusception associated with HSP have been reported.
- Unlike idiopathic intussusception, which predominantly affects the ileo-colic region, HSP-associated intussusception typically originates in the small bowel (ileum or jejunum).
Findings:
- The majority of HSP-related intussusceptions (58.4%) are confined to the small intestine.
- Ileal intussusception accounts for 90% of HSP cases, with jejunal intussusception occurring in 7%.
Implications:
- Understanding the specific patterns of intussusception in HSP is crucial for accurate diagnosis and management.
- The rarity of colo-colic intussusception in HSP highlights the need for careful evaluation, as it deviates from typical presentations.
- Distinguishing HSP-associated intussusception from idiopathic forms is important for appropriate diagnostic and therapeutic strategies, as contrast enema reduction may be less effective in small bowel intussusception.
More Related Videos
09:21A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence
Published on: October 11, 2018
05:45Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Related Concept Videos
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Peptic Ulcer
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Ulcerative Colitis