Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Flash electroretinography and pattern-type visual evoked potentials in early glaucoma]

A Turno-Krecicka1, M H Nizankowska, H Zajac-Pytrus

  • 1Katedry i Kliniki Okulistyki AM we Wrocławiu.

Klinika Oczna
|January 13, 1999
PubMed
Summary

Flash electroretinography (ERG) and pattern-visual evoked potentials (pVEP) show limited diagnostic value for early glaucoma detection. Oscillatory potentials (OPs) may aid research into glaucomatous neuropathy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Progressive outer retinal necrosis syndrome in the course of systemic lupus erythematosus.

Lupus·2016
Same author

Progressive outer retinal necrosis in immunocompromised kidney allograft recipient.

Transplant infectious disease : an official journal of the Transplantation Society·2015
Same author

The role of inflammation in the progression of ocular surface damage in children following allogeneic haematopoietic cell transplantation.

Folia biologica·2013
Same author

[Clinical advantages of colorimetric exploration in the early diagnosis of glaucomatous neuropathy].

Journal francais d'ophtalmologie·2004
Same author

[Pharmacodynamics and pharmacokinetics of prostaglandins and their derivates in eye tissues].

Klinika oczna·2002
Same author

[Management in preretinal macular hemorrhage. Case report].

Klinika oczna·2002

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Electrophysiology

Context:

  • Glaucoma is a leading cause of irreversible blindness.
  • Early diagnosis is crucial for effective management and vision preservation.
  • Current diagnostic methods may not always detect subtle, early-stage glaucomatous changes.

Purpose:

  • To assess the diagnostic sensitivity of flash electroretinography (ERG), oscillatory potentials (OPs), and pattern-visual evoked potentials (pVEP) in identifying early glaucoma.
  • To compare the efficacy of these electrophysiological tests in differentiating between healthy eyes and eyes with various glaucoma subtypes.

Summary:

  • A prospective study evaluated 416 eyes across primary open-angle glaucoma, normal-tension glaucoma, ocular hypertension, and glaucoma-like discs.

Related Experiment Videos

  • Results indicated no significant differences in flash-ERG and pVEP parameters between glaucoma patients and controls.
  • A significant reduction in OPs amplitude was observed specifically in normal-tension glaucoma patients.
  • Impact:

    • Flash-ERG and pVEP demonstrate low diagnostic utility for early glaucoma detection.
    • OPs show potential as a biomarker in scientific research for understanding the pathogenesis of glaucomatous neuropathy.
    • Further investigation into OPs may lead to improved diagnostic or prognostic tools for glaucoma.