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Alpha 2 adrenergic agonists. Neurochemistry, efficacy, and clinical guidelines for use in children
J H Newcorn1, K Schulz, M Harrison
1Division of Child and Adolescent Psychiatry, Mount Sinai Medical Center, New York, New York, USA.
Pediatric Clinics of North America
|January 13, 1999
Abstract:
The alpha 2 adrenergic agonists are used to treat a variety of psychiatric disorders and their usage has been increasing. This article presents the rationale and neurochemical basis for treatment of psychiatric disorders with alpha 2 agents, reviews studies examining clinical efficacy, and develops guidelines for usage. Case vignettes are presented to illustrate how the alpha 2 agents can successfully be used in practice.