Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Advances in approaches to DNA-based diagnostics

D Whitcombe1, C R Newton, S Little

  • 1Zeneca Diagnostics Gadbrook Park Northwich Cheshire CW9 7RA UK. david.whitcombe@diagnostics.zeneca.com.

Current Opinion in Biotechnology
|January 16, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Post-caesarean analgesia: a multicentre retrospective analysis comparing practices in Queensland, Australia (2019-2022).

International journal of obstetric anesthesia·2025
Same author

Adaptive Deep Brain Stimulation in Parkinson's Disease: A Delphi Consensus Study.

medRxiv : the preprint server for health sciences·2024
Same author

HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin.

SLAS discovery : advancing life sciences R & D·2023
Same author

Noncontrast MRI Protocol for Selected Pediatric Pituitary Endocrinopathies: A Procedure with High Diagnostic Yield and Potential to Reduce Anesthesia and Gadolinium-Based Contrast Exposure.

AJNR. American journal of neuroradiology·2021
Same author

Contingent negative variation: a biomarker of abnormal attention in functional movement disorders.

European journal of neurology·2020
Same author

Associations of antenatal maternal psychological distress with infant birth and development outcomes: Results from a South African birth cohort.

Comprehensive psychiatry·2019

Recent DNA diagnostics focus on enhancing existing methods for simpler use and higher throughput. Key advances include simplified genotyping and improved DNA chip technology for faster, more accessible genetic analysis.

Area of Science:

  • Molecular Biology
  • Genetics
  • Biotechnology

Background:

  • DNA diagnostics are crucial for genetic analysis.
  • Advancements in diagnostic techniques are continuously sought.
  • Existing methods often face challenges in usability and throughput.

Purpose of the Study:

  • To summarize recent tangible advances in DNA diagnostics.
  • To highlight improvements in technique simplification and throughput.
  • To discuss the impact of these enhancements on genetic analysis.

Main Methods:

  • Enhancement of existing DNA diagnostic techniques.
  • Development of homogeneous analysis for genotyping.
  • Improvements in DNA chip technology.

Related Experiment Videos

Main Results:

  • Simplified genotyping methods with spectral data output achieved.
  • Miniaturization of diagnostic tools realized.
  • Increased throughput in DNA analysis demonstrated.

Conclusions:

  • Recent progress has made DNA diagnostics more user-friendly.
  • Technological improvements are driving higher efficiency in genetic testing.
  • These advances pave the way for broader application of DNA diagnostics.