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Related Experiment Videos

Gaps--anionic and osmolal

N Smithline, K D Gardner

    JAMA
    |October 4, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Gaps is a bedside diagnostic game with two versions, Anion Gaps and Osmolal Gaps, useful for physicians. These games help identify laboratory errors and metabolic issues by detecting unmeasured anions or osmoles.

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    Area of Science:

    • Clinical Chemistry
    • Nephrology
    • Diagnostic Medicine

    Background:

    • The diagnostic game 'Gaps' is utilized by nephrologists in two distinct versions.
    • It offers valuable insights into patient diagnostics at the bedside.
    • Wider adoption by practicing physicians is recommended for broader clinical utility.

    Observation:

    • The Anion Gaps version detects undetermined anions, signaling potential laboratory errors.
    • It also highlights severe disruptions in serum protein metabolism.
    • This version can indicate the ingestion of specific ionic compounds affecting anion concentrations.

    Findings:

    • The Osmolal Gaps version identifies unmeasured osmoles or increased plasma solids.
    • This can occur in various clinical scenarios.

    Related Experiment Videos

  • It directs attention towards laboratory errors, hyperproteinemia, hyperlipidemia, or unmeasured serum osmoles.

    • Implications:

    • The 'Gaps' game serves as a crucial tool for identifying discrepancies in laboratory results.
    • It aids in diagnosing metabolic disturbances and the presence of exogenous substances.
    • Enhanced utilization can improve diagnostic accuracy and patient management in clinical practice.