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Increased gastroesophageal reflux in infants: can history provide an explanation?
1Department of Pediatrics (MCHK-PE), Tripler Army Medical Center, Honolulu, Hawaii 96859-5000, USA.
Insights
Gastroesophageal reflux (GER) diagnoses in infants have surged, but this may stem from overdiagnosis rather than increased disease prevalence. Changes in infant feeding and sleeping practices are explored as potential contributing factors to this trend.
Area of Science:
- Pediatrics
- Gastroenterology
Background:
- Gastroesophageal reflux (GER) is increasingly cited as a cause of infant illness.
- GER diagnoses in hospitalized infants under one year old have risen over tenfold in recent decades.
Purpose of the Study:
- To investigate the potential relationship between changes in infant rearing practices and the rising rates of GER diagnoses.
- To explore whether increased GER diagnoses reflect a true increase in pathological GER or are due to overdiagnosis.
Main Methods:
- Review of changes in infant feeding (what and how much) over the past 50 years.
- Examination of changes in infant sleeping positions between feedings.
- Analysis of potential links between these rearing factors and GER prevalence.
Main Results:
- The study highlights significant shifts in infant feeding and sleeping environments over the last half-century.
- These changes are posited as potential contributors to the observed increase in GER diagnoses.
Conclusions:
- The rise in GER diagnoses may not solely indicate increased disease incidence.
- Altered infant rearing practices warrant further investigation for their role in GER and related pediatric conditions.
Abstract:
Gastroesophageal reflux (GER), a problem rarely mentioned half a century ago, has now become a major source of blame for a number of pediatric maladies. Over the past few decades, the rate of GER diagnosis in hospitalized infants less than 1 y old rose more than 10-fold. An increased rate of diagnosis does not mean that GER disease is more common. The increase in diagnosis may be the result of overdiagnosis, inappropriate diagnosis or an increased ability to detect GER. However, it is also possible that increased GER diagnosis may reflect a real increase in the prevalence of pathological GER and GER disease. Three aspects of infant rearing have changed dramatically during the past 50 y: what infants are fed, how much they are fed and where they are placed between feedings. This essay examines these aspects of infant rearing and their possible relationship with increased GER.
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