Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Portable blood gas and electrolyte analyzer evaluated in a multiinstitutional study

J Lindemans1, P Hoefkens, A L van Kessel

  • 1Department of Clinical Chemistry, University Hospital Rotterdam, 3000 CA Rotterdam, The Netherlands.lindemans@ckcl.azr.nl

Clinical Chemistry
|January 23, 1999
PubMed
Summary

The SenDx 100 (ABL70) blood gas/electrolyte analyzer demonstrates satisfactory analytical performance for point-of-care testing. Its ease of use and acceptable accuracy meet clinical goals for blood gas and electrolyte analysis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vitamin B12 deficiency after esophagectomy with gastric tube reconstruction for esophageal cancer.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2018
Same author

Early pregnancy maternal and fetal angiogenic factors and fetal and childhood growth: the Generation R Study.

Human reproduction (Oxford, England)·2015
Same author

An optimal periconception maternal folate status for embryonic size: the Rotterdam Predict study.

BJOG : an international journal of obstetrics and gynaecology·2014
Same author

Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate.

Arthritis and rheumatism·2013
Same author

A periconceptional energy-rich dietary pattern is associated with early fetal growth: the Generation R study.

BJOG : an international journal of obstetrics and gynaecology·2012
Same author

Homocysteine and folate concentrations in early pregnancy and the risk of adverse pregnancy outcomes: the Generation R Study.

BJOG : an international journal of obstetrics and gynaecology·2012

Area of Science:

  • Clinical diagnostics
  • Medical instrumentation
  • Point-of-care testing

Background:

  • The SenDx 100 (now ABL70) is a novel blood gas and electrolyte analyzer designed for rapid, near-patient testing.
  • Accurate and efficient analysis of blood gases and electrolytes is crucial for timely clinical decision-making.

Purpose of the Study:

  • To evaluate the performance of the SenDx 100 analyzer in multiple clinical settings.
  • To compare the SenDx 100's precision, accuracy, and patient-sample results against established laboratory bench analyzers.

Main Methods:

  • Multi-center evaluation of the SenDx 100 analyzer.
  • Comparison of imprecision and inaccuracy (via tonometry) with three laboratory bench analyzers.
  • Analysis of approximately 400 patient blood samples.

Related Experiment Videos

Main Results:

  • The SenDx 100 showed better performance (lower CVs) for PO2 and potassium, but slightly worse for pH, PCO2, and ionized calcium compared to bench analyzers.
  • Overall performance met clinical goals (e.g., CLIA '88) across all participating institutions.
  • Mean differences and CVs for patient samples were within acceptable ranges for pH, PCO2, PO2, sodium, potassium, ionized calcium, and hematocrit.

Conclusions:

  • The SenDx 100 (ABL70) analyzer exhibits acceptable analytical performance for blood gas and electrolyte measurements.
  • Its ease of operation and satisfactory accuracy make it suitable for point-of-care and stat laboratory use.