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Updated: Aug 18, 2026

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
Published on: November 25, 2017
Dialyzable sialic acid of toad oviduct
Abstract:
1. Small quantities of dialyzable sialic acid in toad oviduct were found. 2. About one-third of the dialyzable sialic acid reacts directly in the thiobarbituric acid procedure, a finding which suggests that the other two-thirds of the dialyzable sialic acid were probably derived from low molecular weight compounds containing sialic acid. 3. When a soluble fraction was chromatographed on Dowex 1-X4 column, three fractions (I, II and III) were isolated. Peak I was a material which shows identical to authentic NANA, colorimetrically as well as chromatographically. Several studies have indicated that both peaks, II and III, could be sialic acid-bound compounds of low molecular weight.
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