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Related Experiment Videos

Epidemiology of interstitial cystitis: a population based study

G C Curhan1, F E Speizer, D J Hunter

  • 1Department of Medicine, Brigham and Womens' Hospital, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

The Journal of Urology
|January 23, 1999
PubMed
Summary

The prevalence of interstitial cystitis (IC) in the United States is higher than previously thought. This study found IC affects 52-67 per 100,000 women, significantly more than earlier estimates.

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Area of Science:

  • Urology
  • Epidemiology
  • Women's Health

Background:

  • Interstitial cystitis (IC) is a chronic condition with poorly understood epidemiology.
  • Estimating the true prevalence of IC is crucial for understanding its impact.

Purpose of the Study:

  • To estimate the prevalence of interstitial cystitis (IC) among women in the United States.
  • To provide updated epidemiological data for this debilitating syndrome.

Main Methods:

  • Utilized data from 184,583 female participants in the Nurses' Health Study (NHS) I and II.
  • Mailed questionnaires assessed self-reported IC diagnoses, with subsequent medical record review for confirmation.
  • Evaluated the accuracy of self-reported diagnoses using standardized criteria.

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Main Results:

  • 1.4% (NHS II) and 0.4% (NHS I) of participants self-reported IC.
  • Confirmed prevalence rates were 67/100,000 in NHS II and 52/100,000 in NHS I.
  • Prevalence did not significantly vary by age.

Conclusions:

  • The prevalence of interstitial cystitis in the US is over 50% higher than previously reported.
  • US prevalence is approximately three times greater than reported in Europe.
  • Updated prevalence data highlights the significant public health burden of IC.