Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Nutritional aspects of calcium absorption

F Bronner¹, D Pansu

¹Department of BioStructure and Function, The University of Connecticut Health Center, Farmington, Connecticut 06030-3705, USA.

The Journal of Nutrition

|January 23, 1999

Summary

Intestinal calcium absorption varies with intake. Low intake upregulates active duodenal transport, while high intake relies on passive jejunal/ileal absorption, influenced by vitamin D and bioavailability.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Post-denervation renal artery stenosis - a matter of concern?].

Annales de cardiologie et d'angeiologie·2015

Same author

[About an implantable cardioverter-fibrillator].

Annales de cardiologie et d'angeiologie·2011

Same author

An analysis of the role and function of educational reconditioning; with particular reference to the program at Welch Convalescent Hospital.

Occupational therapy and rehabilitation·2010

Same author

A Symbolic Model for the Regulation by Bone Metabolism of the Blood Calcium Level in Rats.

Biophysical journal·2009

Same author

Extracellular and intracellular regulation of calcium homeostasis.

TheScientificWorldJournal·2003

Same author

Coding region of the sorbin gene in different species.

Peptides·2002

Area of Science:

Gastroenterology
Nutritional Science
Human Physiology

Background:

Intestinal calcium absorption is crucial for maintaining calcium homeostasis.
Factors influencing calcium absorption include dietary intake, vitamin D status, and intestinal physiology.

Purpose of the Study:

To elucidate the mechanisms and influencing factors of intestinal calcium absorption.
To differentiate between active and passive calcium transport pathways in various intestinal segments.

Main Methods:

The study reviews existing literature on calcium absorption mechanisms.
It analyzes the roles of habitual calcium intake, bioavailability, and vitamin D in modulating absorption.

Main Results:

Active transcellular calcium transport is upregulated in the duodenum during low calcium intake.
Passive paracellular absorption predominates in the jejunum and ileum with adequate or high calcium intake.
Vitamin D is essential for active calcium transport via calbindin D9k synthesis.

Conclusions:

Intestinal calcium absorption is a dynamic process influenced by intake levels and vitamin D.
Both active and passive mechanisms contribute to calcium absorption, with regional and dietary-dependent variations.
Understanding these mechanisms is vital for addressing calcium deficiencies and optimizing absorption.

Related Experiment Videos