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[Brain cerebrosides and sulfocerebrosides after treatment with hydrocortisone]
L S Chaeva1, M S Suvorova, M A Bespalova
1Sanct-Petersburg State University, Laboratory of Nervous System Biochemistry, Russia.
Abstract:
The influence of the high dose of hydrocortisone on the content of galactocerebrosides, sulfocerebrosides and cholesterol was studied in different regions of growing rat brain. The most distinct alterations in content and relationship of glycolipids were demonstrated in brain hemisphere and cerebellum. The results allow to suggest a conclusion about changes in myelin's lipid metabolism and disturbance of myelinogenesis after high dose hydrocortisone injection.