Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Preschoolers with syphilis

C W Christian1, J Lavelle, L M Bell

  • 1Division of General Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Pediatrics
|January 26, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 stressors, wellbeing and health behaviours: a cross-sectional study.

Journal of public health (Oxford, England)·2021
Same author

Site of PGF<sub>2α</sub> injection does not alter effectiveness of the Select Synch + controlled internal drug release and timed artificial insemination protocol.

Theriogenology·2016
Same author

Making strides towards better mental health care in Peru: Results from a primary care mental health training.

International journal of clinical psychiatry and mental health·2016
Same author

Six-year follow-up of a point-source exposure to CWD contaminated venison in an Upstate New York community: risk behaviours and health outcomes 2005-2011.

Public health·2014
Same author

Injury to the proximal deep medial collateral ligament: a problematical subgroup of injuries.

The Journal of bone and joint surgery. British volume·2010
Same author

The newer technic of intracapsular cataract extraction.

The Journal of the American Osteopathic Association·2010
Same journal

Severe Postoperative Hypernatremia in an Adolescent Following Sleeve Gastrectomy.

Pediatrics·2026
Same journal

Barriers to Implementing SMART for Asthma in Pediatric Primary Care.

Pediatrics·2026
Same journal

Blood Lead Testing Among Children Enrolled in Medicaid.

Pediatrics·2026
Same journal

From Screening to Support: Crafting Social Needs Response Systems That Work for Families.

Pediatrics·2026
Same journal

A Social Care Intervention in Pediatric Practices: A Stepped Wedge Cluster Trial.

Pediatrics·2026
Same journal

Pediatric Cheerleading-Related Head Injuries and the "Double Down" Rule Change.

Pediatrics·2026
See all related articles

Syphilis in preschoolers is a growing concern, with three cases highlighting diagnostic challenges. Identifying the source of infection and distinguishing congenital from acquired syphilis in young children is difficult.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health Epidemiology
  • Clinical Dermatology

Background:

  • Syphilis incidence is rising in adult and pediatric populations.
  • Syphilis in preschoolers is underrepresented in current medical literature.
  • Challenges exist in diagnosing and managing syphilis in young children.

Observation:

  • Three preschool-aged children (3-4 years) were diagnosed with syphilis.
  • Clinical presentations varied, including nephrosis, secondary syphilis with rash, and subtle late congenital infection signs.
  • Sources of infection were difficult to ascertain, with likely sexual abuse suspected in all cases.

Findings:

  • Diagnostic difficulties include differentiating acquired from congenital syphilis.
  • Challenges involve recognizing clinical signs, obtaining histories from young children, and interpreting prenatal/neonatal testing.

Related Experiment Videos

  • Inadequate follow-up and evolving treatment guidelines complicate management.

    • Implications:

    • Physicians must be vigilant for syphilis in preschoolers due to increasing prevalence.
    • Improved diagnostic and evaluation guidelines are needed for young children.
    • Addressing challenges in interviewing child sexual abuse victims is crucial for protection and care.