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Related Concept Videos

In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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Related Experiment Video

Updated: Jun 29, 2026

Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice
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Published on: April 2, 2020

Preparation of knockout mice

J Osada1, N Maeda

  • 1Department of Biochemistry and Cellular Biology, Facultad de Veterinaria, Universidad de Zaragoza, Spain.

Methods in Molecular Biology (Clifton, N.J.)
|January 26, 1999
PubMed
Summary

No abstract available in PubMed .

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