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Omeprazole and the development of acute hepatitis
S I Koury1, C K Stone, D D La Charité
1Department of Emergency Medicine, University of Kentucky School of Medicine, Lexington 40536, USA.
Abstract:
Omeprazole has been used with increasing frequency for the treatment of conditions such as reflux oesophagitis, peptic ulcer disease, and Zollinger-Ellison syndrome. Several sequelae have been documented in the literature, but there has been limited indication of significant hepatotoxicity. We present a unique case of acute hepatitis secondary to the use of omeprazole that was resolved spontaneously with discontinuation of the drug.