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Schistosomiasis and associated infections

J R Lambertucci1, A A Rayes, J C Serufo

  • 1Departamento de Clínica Médica, Faculdade de Medicina, ICB, UFMG, Belo Horizonte, Brasil. lamber@net.em.com.br

Memorias Do Instituto Oswaldo Cruz
|January 28, 1999
PubMed
Summary

Schistosomiasis infection is linked to various other infections, including viral hepatitis B, Salmonella bacteraemia, Staphylococcus aureus liver abscesses, and acquired immunodeficiency syndrome (AIDS). This paper updates current data on these associations.

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Area of Science:

  • Infectious Diseases
  • Parasitology
  • Hepatology

Background:

  • Schistosomiasis is a parasitic disease with complex interactions with other infections.
  • Previous studies show conflicting results regarding the association between schistosomiasis and viral hepatitis B.
  • Established links exist between schistosomiasis and Salmonella bacteraemia, Staphylococcus aureus liver abscesses, and emerging evidence suggests a connection with acquired immunodeficiency syndrome (AIDS).

Purpose of the Study:

  • To update current data on the associations between schistosomiasis and various bacterial and viral infections.
  • To consolidate evidence on the role of schistosomiasis as a potential facilitator for other infectious diseases.

Main Methods:

  • Review and synthesis of existing literature and epidemiological data.

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  • Analysis of hospital-based and field-based study findings.
  • Inclusion of recent evidence on schistosomiasis and AIDS interactions.
  • Main Results:

    • Hospital-based studies frequently report viral hepatitis B in association with schistosomiasis, though field studies have not consistently confirmed this.
    • A well-documented association exists between schistosomiasis and Salmonella bacteraemia.
    • Schistosomiasis is implicated as a facilitating factor in Staphylococcus aureus liver abscesses, and new evidence points to an interaction with AIDS.

    Conclusions:

    • Schistosomiasis exhibits significant associations with a range of infectious agents, influencing their prevalence and pathogenesis.
    • Further research is warranted to clarify the mechanisms underlying these complex host-parasite interactions.
    • Understanding these associations is crucial for public health strategies in endemic regions.