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Middle aortic syndrome treated by stent implantation
G Brzezinska-Rajszys1, S A Qureshi, J Ksiazyk
1Catheterisation Laboratory, Children's Memorial Health Institute, Al Dzieci Polskich 20, 04-736 Warsaw-Miedzylesie, Poland.
Heart (British Cardiac Society)
|January 29, 1999
Summary
Stent implantation effectively treats middle aortic syndrome, reducing pressure gradients and improving blood pressure control in pediatric patients. This minimally invasive approach is a promising alternative to surgery, requiring further investigation.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Middle aortic syndrome is a rare condition characterized by stenosis of the aorta, often leading to hypertension.
- Traditional surgical interventions carry significant risks, particularly in pediatric patients.
Purpose of the Study:
- To evaluate the outcomes of stent implantation for treating middle aortic syndrome in children.
- To assess the efficacy and safety of endovascular repair in this patient population.
Main Methods:
- A prospective case series involving five pediatric patients (aged 4-17 years) with middle aortic syndrome.
- Stent implantation in the mid/lower thoracic or upper abdominal aorta.
- Assessment of pressure gradients, blood pressure control, and imaging for complications.
Main Results:
- Successful stent deployment and significant reduction in aortic pressure gradients (from mean 63.2 mm Hg to 13.6 mm Hg) post-implantation.
- Good blood pressure control achieved in four out of five patients at a mean follow-up of 12.2 months; one patient became normotensive.
- No aneurysm formation observed; one case of stent thrombosis successfully managed with thrombolysis and re-stenting.
Conclusions:
- Stent implantation is a safe and effective alternative to surgery for middle aortic syndrome in children.
- Endovascular treatment offers favorable outcomes and warrants further clinical evaluation.