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Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes
N S Duesbery1, G F Vande Woude
1ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, MD 21702, USA.
Biology of the Cell
|January 29, 1999
Abstract:
The title of this article is taken from a 1971 publication by Yoshio Masui and Clement Markert in which they describe the discoveries of the meiotic regulatory activities maturation promoting factor and cytostatic factor. Here we review the experiments that led to these discoveries and discuss their relation to our current knowledge of the biochemistry of oocyte maturation.