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[A method for reducing the risk of infection in newborn and premature infants with stomas]
Insights
Continuous extracorporeal stool transport (CEST) significantly reduced sepsis risk in newborns with stomas. This technique prevents bacterial translocation and short bowel syndrome, improving outcomes for premature infants.
Area of Science:
- Neonatal surgery
- Pediatric gastroenterology
- Sepsis prevention
Context:
- Premature infants and neonates with stomas face high sepsis risk.
- Parenteral nutrition exacerbates this risk due to bacterial translocation.
- 35 newborns with ileo- or jejunostomas were studied.
Purpose:
- To evaluate the efficacy of continuous extracorporeal stool transport (CEST) in preventing sepsis.
- To prevent distal bowel disuse and short bowel syndrome in neonates with stomas.
Summary:
- The continuous extracorporeal stool transport (CEST) technique rerouted proximal bowel content to the distal stoma.
- This intervention was applied a few days post-surgery in 35 newborns.
- Sepsis rates decreased from 9 to 0.8 cases per 1000 days with CEST.
Impact:
- CEST significantly reduced sepsis incidence in neonates with stomas.
- The technique mitigates risks associated with bacterial translocation and short bowel syndrome.
- Improved outcomes for high-risk neonatal surgical patients.
Abstract:
Prematures and neonates with stomas have a high risk of developing sepsis by bacterial translocation, particularly when combined with parenteral nutrition. We studied a group of 35 newborns where split ileo- or jejunostomas were implanted in their first week of life. To prevent the development of a non-used distal bowel and a short bowel syndrome, the proximal bower content was transferred into the aboral stoma via the new continuous extracorporal stool transport (CEST) technique a few days after surgery. By using CEST the sepsis rate was reduced from 9 (without CEST) to only 0.8 cases of sepsis in 1000 days.