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Bilateral acute retinal necrosis caused by cytomegalovirus in an immunocompromised patient
E K Akpek1, C Kent, F Jakobiec
1Department of Immunology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
American Journal of Ophthalmology
|February 5, 1999
Abstract
Purpose:
To report a case of bilateral acute retinal necrosis caused by cytomegalovirus.
Methods:
A diagnostic vitrectomy was performed on a patient with non-Hodgkin lymphoma who presented with a bilateral, rapidly progressing necrotizing retinitis and uveitis.
Results:
Immunohistochemical studies and polymerase chain reaction disclosed cytomegalovirus as the cause of retinitis. The patient was treated with intravitreal and intravenous ganciclovir.
Conclusions:
Although rare, cytomegalovirus may lead to an appearance identical to acute retinal necrosis and should be considered among the viral etiologies of this syndrome.