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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
Experience with transurethral incision of ureteroceles
1Department of General Surgery, Division of Urology, Duke University Medical Center, Durham, N.C., USA.
Insights
Transurethral incision for ureteroceles in children offers initial decompression but often requires further surgery. This endoscopic approach is best for specific cases like urosepsis or severe reflux, not as a definitive long-term solution.
Area of Science:
- Pediatric Urology
- Endourology
- Pediatric Surgery
Background:
- Ureteroceles are congenital anomalies requiring surgical consideration in infants and children.
- Primary transurethral ureterocele incision is a minimally invasive option explored for treatment.
Purpose of the Study:
- To investigate the efficacy and long-term outcomes of primary transurethral ureterocele incision in pediatric patients.
- To determine the role of this endoscopic approach as a definitive treatment for ureteroceles.
Main Methods:
- Retrospective review of 13 pediatric patients (2 weeks to 8 years) undergoing transurethral incision for 14 ureteroceles.
- Analysis of patient charts and radiographic studies to assess outcomes.
Main Results:
- Successful decompression achieved in 93% of ureteroceles.
- Improvement or resolution of hydronephrosis in 71.4% of cases.
- 38% of patients required subsequent reconstructive surgery for complications like reflux or infection.
Conclusions:
- Transurethral incision provides temporary decompression for pediatric ureteroceles but has a limited role as definitive treatment.
- Indications include urosepsis, prolapsing ureteroceles with obstruction, or massive reflux.
- Allows for reevaluation of renal segment function and facilitates future reconstructive surgery.
Objectives:
The value of primary transurethral ureterocele incision was investigated in the treatment of ureteroceles in infants and children.
Methods:
The charts and radiographic studies of 13 patients between the ages of 2 weeks and 8 years who underwent transurethral incision of 14 ureteroceles as primary surgical therapy at our institution were reviewed.
Results:
57% of the ureteroceles were intravesical and 43% extravesical. 64.3% were associated with the upper pole of a duplicated system. All 14 ureteroceles were associated with a functional renal moiety. Endoscopic incision achieved ureterocele decompression in 13 of 14 ureteroceles (93%). Preexisting hydronephrosis improved or resolved in 10 of 14 cases (71.4%). Renal function after decompression was not shown to be significantly altered or improved. 5 of 13 patients (38%) required definite surgical reconstruction for recurrent urinary tract infections, upper pole vesicoureteral reflux, hydronephrosis and lower pole vesicoureteral reflux within a mean follow-up period of 14 months.
Conclusion:
Transurethral incision has a limited role in the treatment of ureteroceles in children. In many or even most cases it cannot be expected to constitute long-term definite treatment for ureteroceles. It is mainly indicated in patients with urosepsis, prolapsing ureteroceles with functional bladder neck obstruction or massive reflux into other renal segments. In these settings it reliably achieves decompression and allows effective treatment of infection. The function of the previously obstructed renal segment can be reevaluated at later point in time to assess whether it should be saved. The delay permits interim growth that is likely to make bladder reconstruction easier.
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