Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The MIRD perspective 1999. Medical Internal Radiation Dose Committee

R W Howell1, B W Wessels, R Loevinger

  • 1Department of Radiology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, USA.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|February 6, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of a walnut-rich breakfast on cognitive performance and brain activity throughout the day in healthy young adults: a crossover intervention trial.

Food & function·2025
Same author

Exploring the experiences of UK-based private physiotherapists when running and progressing a physiotherapy business: a hermeneutic phenomenological study.

Physiotherapy·2024
Same author

Excitons in CsPbBr<sub>3</sub> Halide Perovskite.

The journal of physical chemistry letters·2021
Same author

ICRP Publication 140: Radiological Protection in Therapy with Radiopharmaceuticals.

Annals of the ICRP·2019
Same author

Building and environmental factors that influence bacterial and fungal loading on air conditioning cooling coils.

Indoor air·2018
Same author

Current perspective on actinic keratosis: a review.

The British journal of dermatology·2016
Same journal

Overall Survival with [<sup>177</sup>Lu]Lu-PSMA-617 Versus [<sup>177</sup>Lu]Lu-PSMA I&T: A Propensity Score-Matched Real-World Analysis.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Toward a Biopsy-Free Diagnosis of Prostate Cancer: Potential of Combined <sup>18</sup>F-Flotufolastat PSMA PET and mpMRI.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

PSMA PET/CT-Targeted Biopsy in Men with Negative or Equivocal Multiparametric MRI and Exploratory Dynamic Total-Body PET: The FUPERMAN Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Erratum.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Live from 2026 SNMMI Annual Meeting in Los Angeles!

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

CAR T-Cell Therapy for Cancer: Updates and Challenges for Response Assessment.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
See all related articles

The Medical Internal Radiation Dose (MIRD) schema offers versatile tools for internal radiation dosimetry. It now extends to cellular and suborgan levels, providing advanced methods for accurate dose calculations.

Area of Science:

  • Medical Physics
  • Radiological Sciences
  • Nuclear Medicine

Background:

  • The Medical Internal Radiation Dose (MIRD) schema is a foundational framework for internal radiation dosimetry.
  • Traditionally applied to organ-level dosimetry, its adaptability to finer scales is increasingly recognized.

Purpose of the Study:

  • To highlight the expanded applicability of the MIRD schema beyond organ dosimetry.
  • To introduce new tools and techniques derived from the MIRD schema for advanced radionuclide dosimetry.

Main Methods:

  • The study discusses the application of the MIRD schema across various biological scales, from organs to cellular levels.
  • It references recent MIRD pamphlets and a monograph focusing on cellular dosimetry.
  • New dosimetry tools are presented, including a dynamic bladder model and voxel S values.

Related Experiment Videos

Main Results:

  • Demonstrates the flexibility of the MIRD schema for dosimetry at suborgan, multicellular, and cellular levels.
  • Introduces novel dosimetry tools such as the dynamic bladder model and voxel S values for 3D dose distributions.
  • Highlights techniques for acquiring quantitative distribution and pharmacokinetic data essential for dosimetry.

Conclusions:

  • The MIRD schema is a flexible and powerful approach applicable to diverse dosimetry needs, from organs to cellular levels.
  • Recent advancements provide sophisticated tools for radionuclide dosimetry, enhancing accuracy and detail.
  • The expanded MIRD framework supports detailed dose assessment in various biological structures and scales.