Related Experiment Video
Updated: Aug 2, 2026

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
Published on: July 29, 2012
Immune responses in chickens against Eimeria tenella sporozoite antigen
R Garg1, D P Banerjee, S K Gupta
1Department of Veterinary Parasitology, CCS Haryana Agricultural University, Hisar, India.
Abstract:
Two-day old broiler chicks were subcutaneously immunized with Eimeria tenella sporozoite antigen (25 microg per chick) with or without adjuvants on 2 and 18 days of age and the effect of induced immunity was determined by challenging the chickens with 10(4) homologous sporulated oocysts at 32 days of age. Chicks immunized with sporozoite antigen emulsified in Freund's Complete Adjuvant (FCA) showed protection in terms of oocyst production, mortality and mean lesion scores. Antigen emulsified in FCA produced significant cell mediated immune responses (as assessed by lymphocyte migration inhibition test) from 12 to 30 days post-immunization. Antibody responses as assessed by enzyme linked immunosorbent assay were significant from 12 days postimmunization when the antigen was administered with or without adjuvants by subcutaneous route.
Related Concept Videos
Humoral Immune Responses
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Cross-reactivity
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Chickenpox

